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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0664 All Species: 19.09
Human Site: T1178 Identified Species: 35
UniProt: O75153 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75153 NP_056044.3 1309 146670 T1178 E G Y T I Y K T Q L G E D H E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548323 1501 166268 T1370 E G Y T V Y K T Q L G E D H E
Cat Felis silvestris
Mouse Mus musculus Q5SW19 1315 148050 T1180 E G Y T I Y K T Q L G E D H E
Rat Rattus norvegicus XP_001080615 1352 151608 T1221 E G Y T I Y K T Q L G E D H E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509391 982 108607 F860 Q A K V Q Q G F L K E G C E L
Chicken Gallus gallus XP_415920 1293 145294 K1171 N A L A I S S K Y H G S K S L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A0JMD0 1400 155792 L1276 K A E F R S A L Q H E K E G Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAB5 1448 160833 S1303 E T Y S F Y K S Q L G E N H E
Honey Bee Apis mellifera XP_624898 1290 145677 T1168 S Y H L V A R T Q S C M G D F
Nematode Worm Caenorhab. elegans P34466 1247 139903 I1121 T G L I S N L I A R T H A A R
Sea Urchin Strong. purpuratus XP_001198284 1101 124381 L979 K L G V Q L L L R D Y D L D S
Poplar Tree Populus trichocarpa XP_002314020 1343 146561 K1131 K T Y D I L V K Q L G E E D S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RY84 1211 135142 K1066 E S L R V C N K V F G E Q T V
Conservation
Percent
Protein Identity: 100 N.A. N.A. 83.3 N.A. 94.9 89.9 N.A. 60.8 83.1 N.A. 75 N.A. 52 59.8 39.9 51.9
Protein Similarity: 100 N.A. N.A. 85.5 N.A. 96.9 92.7 N.A. 67.2 89.3 N.A. 83.6 N.A. 69 75.7 59.5 63.7
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 100 100 N.A. 0 13.3 N.A. 6.6 N.A. 66.6 13.3 6.6 0
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 6.6 13.3 N.A. 26.6 N.A. 86.6 33.3 6.6 20
Percent
Protein Identity: 27.3 N.A. N.A. N.A. N.A. 29
Protein Similarity: 46.6 N.A. N.A. N.A. N.A. 48.9
P-Site Identity: 40 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 53.3 N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 24 0 8 0 8 8 0 8 0 0 0 8 8 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 8 0 8 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 8 0 8 31 24 0 % D
% Glu: 47 0 8 0 0 0 0 0 0 0 16 54 16 8 39 % E
% Phe: 0 0 0 8 8 0 0 8 0 8 0 0 0 0 8 % F
% Gly: 0 39 8 0 0 0 8 0 0 0 62 8 8 8 0 % G
% His: 0 0 8 0 0 0 0 0 0 16 0 8 0 39 0 % H
% Ile: 0 0 0 8 39 0 0 8 0 0 0 0 0 0 0 % I
% Lys: 24 0 8 0 0 0 39 24 0 8 0 8 8 0 0 % K
% Leu: 0 8 24 8 0 16 16 16 8 47 0 0 8 0 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 8 0 0 0 0 8 8 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 16 8 0 0 62 0 0 0 8 0 0 % Q
% Arg: 0 0 0 8 8 0 8 0 8 8 0 0 0 0 8 % R
% Ser: 8 8 0 8 8 16 8 8 0 8 0 8 0 8 16 % S
% Thr: 8 16 0 31 0 0 0 39 0 0 8 0 0 8 0 % T
% Val: 0 0 0 16 24 0 8 0 8 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 47 0 0 39 0 0 8 0 8 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _